Synthesis of 2-Trifluoromethyl Quinoline by the Reaction of Fluorinated Imine with Alkyne Catalyzed by Indium(III) Triflate

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Synthesis of 2-Trifluoromethyl Quinoline by the Reaction of Fluorinated Imine with Alkyne Catalyzed by Indium(III) Triflate

Synlett
DOI: 10.1055/s-0030-1258770

Abstract

Preparation of 2-trifluoromethyl-4-aryl quinolines from a variety of readily available alkynes and N-aryl trifluoroethylimine has been achieved via indium(III) triflate catalyzed Diels-Alder reactions.
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